Vivigen Banner Image

ViviGen Cellular Bone Matrix and ViviGen MIS Delivery System

ViviGen®  and ViviGen Formable®

ViviGen represents a paradigm shift in the field of bone repair and tissue engineering by focusing on lineage committed bone cells. At every step of ViviGen’s processing, LifeNet Health has focused on maintaining the highest level of bone cell viability.

ViviGen is a Human Cells, Tissues, and Cellular and Tissue-based Product (HCT/P) comprised of cryopreserved viable, lineage committed bone cells within a corticocancellous bone matrix and demineralized bone delivering all three properties necessary for bone formation.

ViviGen and ViviGen Formable provide the same advantages as autograft to meet surgeons’ clinical needs. Learn more in the case study and literature section about the science and the growing body of clinical evidence supporting ViviGen and ViviGen Formable cellular bone matrix for both spine, trauma, extremities and craniomaxillofacial (CMF) applications.

ViviGen is the first cellular allograft to focus on recovering, processing, and protecting viable, lineage committed bone cells. It is comprised of viable, cryopreserved corticocancellous bone matrix and demineralized bone. These three components of ViviGen provide the properties necessary for bone repair that include osteoinductive signals, osteoconductive bone scaffolds, and osteogenic cells.

Technical Monograph

Minimizing Immune Potential of ViviGen

Characterization of ViviGen Formable Fiber Technology

ViviGen®  MIS

Designed for efficiency in minimally invasive surgical procedures, ViviGen MIS is more than three times faster than traditional methods of graft delivery. This addition to the ViviGen portfolio includes a cannula containing the allograft bone material and a delivery dispenser to quickly express the graft material. 

ViviGen MIS Surgical Technique Guide

Comparison of Graft Preparation and Delivery Performance Between the ViviGen® MIS Graft Delivery System and a Bone Graft Funnel

Osteogenic

Osteogenic processing removes bone marrow components including mesenchymal stem cells while retaining desirable bone cells (osteoblasts, osteocytes, and bone lining cells)

Osteoconductive

Osteoconductive provides a natural scaffold for cell attachment, migration, and proliferation

Osteoinductive

Osteoinductive patented demineralization process exposes the natural growth factors within the bone matrix that recruit host cells and stimulate bone forming activity