Preservon®: The Future of Graft Preservation Technology

Unlock the Power of Preservon for Allograft Storage

Preservon is an innovative preservation technology developed by LifeNet Health, designed to facilitate the storage and handling of allograft tissues. This method addresses common challenges associated with traditional graft preservation techniques, such as freezing and freeze-drying.

Ambient Temperature Storage

The ability to store grafts at ambient temperatures allows for more straightforward logistics in shipping and handling, as it does not require dry ice or specialized freezers.

 

Rapid Preparation for Use

Grafts preserved with Preservon can be utilized immediately or rinsed and used 30 seconds after opening based on the procedure. This rapid preparation minimizes delays in surgical procedures that often arise from thawing or rehydrating traditional frozen or freeze-dried grafts.

 

Moisture Retention

The technology employs a glycerol-based solution, which replaces free-standing water molecules within the grafts. Glycerol functions as a humectant, maintaining moisture levels and preventing the brittleness that can occur with other preservation methods. 

 

Benefits of Glycerol-Based Preservation:

 

Convenient Shipping and Storage

The ability to store grafts at ambient temperatures allows for more straightforward logistics in shipping and handling, as it does not require dry ice or specialized freezers.

Preservation of Tissue Integrity

Grafts preserved using Preservon retain their biomechanical and biochemical properties, which reduces the risk of brittleness and maintains functionality upon implantation.1

Efficiency in Surgical Preparation

By eliminating the need for time-consuming rehydration or thawing processes, Preservon can enhance operational efficiency in surgical settings. Grafts can be prepared quickly and can be used immediately, although rinsing prior to implantation is optional based on surgical preference.

 

Applications of Preservon:

Preservon technology is applicable to a range of graft types, including bone and soft tissue allografts.

 

Preservon Peer-Reviewed Publications

Preservon represents an advancement in graft preservation technology. By addressing the limitations of traditional methods, such as the need for freezing or extensive preparation, it contributes to improved usability and efficiency in clinical environments. This technology provides healthcare professionals with reliable graft options while enhancing the overall experience for patients undergoing procedures involving allografts. 

 

Select Peer-Reviewed Publications

Preservation of allograft bone using a glycerol solution: a compilation of original preclinical research.
Samsell B, Softic D, Qin X, McLean J, Sohoni P, Gonzales K, Moore MA. Biomater Res. 2019 Feb 13;23:5. doi: 10.1186/s40824-019-0154-1

Evaluation of glycerol-preserved bone allografts in cervical spine fusion: a prospective, randomized controlled trial.
Graham RS, Samsell BJ, Proffer A, Moore MA, Vega RA, Stary JM, Mathern B. J Neurosurg Spin. 2015 Jan;22(1):1-10. doi: 10.3171/2014.9.SPINE131005

Comparison of Fusion Rates between Glycerol-Preserved and Frozen Composite Allografts in Cervical Fusion.
Rodway I, Gander J. Int Sch Res Notices. 2014 Oct 28;2014:960142. doi: 10.1155/2014/960142

References

1. Samsell B, Softic D, Qin X, McLean J, Sohoni P, Gonzales K, Moore MA. Preservation of allograft bone using a glycerol solution: a compilation of original preclinical research. Biomater Res. 2019 Feb 13;23:5. doi: 10.1186/s40824-019-0154-1