The CardioGraft® portfolio of cryopreserved and decellularized allografts offers surgeons a safe and reliable solution for cardiac repair and reconstruction. Human allografts have shown to have a natural resistance to infection and can be used directly in infected surgical fields. For patients who present with an infection or those who are susceptible to infection, a cardiac allograft may be the safest choice for cardiac repair and reconstruction.1-6
Aortic & Pulmonary Valve Replacement
Allograft aortic valves are effective for replacing infected native and prosthetic valves, as allograft tissue is naturally resistant to infection. Allograft pulmonary valves are ideal for adult congenital RVOT reconstruction and pediatric valve replacement. Both valve types allow patients to live actively without the burden of lifelong anticoagulation therapies.
Conduit Repair & Reconstruction
Allograft conduits are proven solutions for cardiac repair and reconstruction. They are also effective against graft infections as allografts are naturally resistant to infections.
Congenital Defect Repair
Allograft patch grafts are utilized in repair of the right ventricular outflow tract and congenital outflow tract anomalies. Patch grafts are available both cryopreserved and decellularized utilizing our patented Matracell technology.
1. Kirklin et al. Aortic Valve Endocarditis with Aortic Root Abscess Cavity: Surgical Treatment with Aortic Valve Homograft. Ann Thorac Surg 45:674-677, June 1988
2. Tuna et al. Results of Homograft Aortic Valve Replacement for Active Endocarditis. Ann Thorac Surg 1990; 49: 619-24
3. Hopkins et al. Cardiac Reconstructions with Allograft Tissues. Springer 2005
4. Pettersson, Coselli, et al. 2016 The American Association for Thoracic Surgery (AATS) consensus guidelines: Surgical treatment of infective endocarditis. Journal of Thoracic and Cardiovascular Surgery, 2017; 153: 1241-1258
5. Lofland GK, et al. Initial pediatric cardiac experience with decellularized allograft patches. Ann of Thoracic Surg, 2012;93:968-71
6. Hopkins RA, et al. Pulmonary Arterioplasty With Decellularized Allogeneic Patches. Ann of Thoracic Surg, Vol. 97, Issue 4, April 2014, Pages 1407-1412